Endocrine Abstracts

Background: Thyroid carcinomas are the most frequent endocrine malignancies of which more than nighty percent are differentiated thyroid carcinomas (DTC). It’s known that genetic variation plays 75% role in the development of papillary thyroid carcinoma (PTC).Material and methods: In a case control setting subjects between January 2005 and December 2015 were evaluated for inclusion in the study. We aimed to compare the genotype frequency distributio...

Background: Exercise training has become an important adjunct therapy for both the prevention and management of type II diabetes mellitus. Interest in telemedicine is increasing as a potentially innovative and sustainable intervention approach to diabetes management. Telemedicine can facilitate the achievement of individualized treatment goals by training patients to manage their own disease.Objective: To evaluate the effect of telemedicine on exercise c...

Introduction: Increased neutrophil to lymphocyte ratio (NLR) is an inflammatory marker and an indicator of cardiovascular risk. Recent studies demonstrated that the NLR values of the diabetic patients were significantly higher than the healthy controls. Vitamin D (25OHD) deficiency has been associated with diabetes mellitus and cardiovascular diseases. Studies established a significant negative correlation between 25(OH)D and HbA1c levels. Aim of this study is to evaluate the ...

Introduction: Because of their anti-inflammatory effect, topical corticosteroids are widely used in dermatological diseases. Topical use is typically safe, but serious adverse effects induced by systemic absorption are occasionally reported. We report a patient who developed Cushing’s syndrome due to long-term misuse of topical bethametasone and clobetasol.Case Report: A 24-year-old man presented with rapid weight gain and purple strias in multiple ...

Introduction: Primary hyperparathyroidism (PHPT) is usually characterized by overproduction of parathormone (PTH) due to a solitary parathyroid adenoma. Its treatment involves surgical removal of the solitary adenoma or hyperplastic parathyroid glands that secrete PTH. Medical treatment options are used for patients with conditions that preclude surgical operation.Case presentation: A 57-year-old female patient underwent left total and right subtotal thy...

Introduction: Fahr disease, is a rare pathology characterized by neuropsychiatric symptoms and bilateral symmetrical intracranial, especially basal ganglial calcifications. Although the exact etiology is not known, it is often associated with calcium and phosphorus metabolism disorders. We aim to present two brothers who presented with Fahr’s disease which is a rare condition.Case: Sixty-year-old male patient without a medical history of ilness was ...

Introduction: Acromegaly patients are known to have an increased risk of malignancies. This may be as a result of the effect of insulin-like growth factor I (IGF-I) on cellular proliferation and apoptosis inhibition. Although there are various reports related with hematological malignancies in children who treated with growth hormone (GH), few data are available about hematological malignancies in acromegaly patients. Here, we report a patient with acromegaly who has been deve...

Introduction: Rathke’s cleft cyst is one of the pituitary non-adenomatous tumors that found in about 20% of pituitary glands at autopsy. Symptomatic Rathke’s cleft cysts are rarely, but these cysts can cause serious medical problems associated with compression of the pituitary gland, pituitary stalk, optic nerve or hypothalamus. Here, we report a rare case of 73 years old man with sudden onset headache due to Rathke’s cleft cyst present with symptoms and radiolo...

Introduction: Ectopic and atypically localized parathyroid adenomas such as in the anterior mediastinum, paraesophageal or retrotracheal position, although rare, can be seen in clinical practice. Ultrasound (US) which is a frequently used and one of the best conventional imaging modality sometimes fails to identify the lesion especially in atypically localized adenomas. Endoscopic US (EUS) is a new technique that can be used for localization of parathyroid lesions. We reported...

Introduction: Parathyroid lipoadenoma (PLA) is a rarely seen, benign variant of parathyroid adenoma (PA). However, PA usually consists of uniform, polygonal chief cells with a few nests of oxyphil cells, PLA consists of similar histologic features, but with an abundance of fat cells. Additionally, PLA may be functional with the secretion of parathyroid hormone (PTH) or non-functional. Here, we present a case of atypical PLA presented with severe hypercalcemia and skeletal defo...